KBSI 연구장비공동활용 장비상세조회
네비게이션 바로가기 본문 바로가기

기기검색

장비 상세조회

메트릭스 보조레이저탈착 질량분석기 이미징 시스템
Matrix-Assisted Laser Desorption Ionization-Mass Spectrometer Imaging System

분석장비 상세내역
영문약어 MALDI / MS
장비명(한글) 메트릭스 보조레이저탈착 질량분석기 이미징 시스템 
기기코드 AS21
연구장비표준분류
기기상태 양호 
AS21.jpg

부서 및 장비담당자

부서 및 장비담당자
지역 오창본원 
주소 (28119)
충청북도 청주시 청원구 오창읍 연구단지로 162 한국기초과학지원연구원 
보유센터 및 부서 오창본원 연구장비운영부 
장비담당자 최정훈  박문희  조건  
전화  
팩스 043-240-5158 
메일  

Spec 및 활용분야

Spec 및 활용분야
원리 및 특징
    · 분자량이 비교적 큰 시료와 매트릭스가 혼합된 결정에 순간적으로 레이저를 조사하여 이온화시킨 후, 이온들을 비행시간형 질량분석기를 통과시켜 검출기까지의 도달시간을 측정하여 분자량을 얻는다.
구성 및 성능
    ○ 질량한계:>300,000Da(upper limit ser by suitably ionized biomolecule)
    ○ 질량분별능: Delayed extraction mode Linear mode: >80 for BSA(5pmol/㎕), >1000 for Myoglobin(5pmol/㎕) >3000 ○ for angiotensin I (1pmol/㎕) Reflector mode: >15,000 for Bovine insulin(5pmol/㎕) >1,200 for E.coli
    ○ 이온화법: MALDI with N₂laser(337nm,3ns pulse; Samrt Beam Laser)
    ○ 분석관: 비행시간형 질량분석기
    ○ TOF/TOF를 이용한 high-energy MS/MS 가능
활용분야
    고분해능 질량분석기를 이용한 고분자 합성시료 및 생체물질 (단백질, 핵산, 탄수화물 등) 분자량측정 및 정성분석

장비 공지사항


연관논문

Comparative N-Linked Glycan Analysis of Wild-Type and α1,3-Galactosyltransferase Gene Knock-Out Pig Fibroblasts Using Mass Spectrometry Approaches
김병기
MOLECULES AND CELLS, 2015
Detection of Hanganutziu Deicher antigens in O-glycans from pig heart tissues by matrix-assisted laser desorptionionization time-of-flight mass spectrometry
김병기
XENOTRANSPLANTATION, 2013
Ligand-to-ligand charge transfer in heteroleptic Ir-complexes: comprehensive investigations of its fast dynamics and mechanism†
Yang-Jin Cho,a So-Yoen Kim,a Minji Cho,a Kyung-Ryang Wee,b Ho-Jin Son,a
PHYSICAL CHEMISTRY CHEMICAL PHYSICS, 2016
Anti-inflammatory action of an antimicrobial model peptide that suppresses the TRIF-dependent signaling pathway via inhibition of toll-like receptor 4 endocytosis in lipopolysaccharide-stimulated macrophages
심도완,허강혁,김영규,심은정,강태봉,최재완,심대원,정선희,이승홍,방정규,원형식,이광호
PLoS One, 2015
Electrochemical Deposition of End-Capped Triarylamine and Carbazole Dendrimers: Alternate Technique for the Manufacture of Multilayer Films.
손호진, 한원식, 이국화, 정하진, 이종목, 고재중, 강상욱
Chemistry of Materials, 2009
End-Capped Silole Dendrimers on a Carbosilane Periphery: Potential Electroluminescent Materials
손호진, 한원식, 김효정, 김정균, 고재중, 이종목, 강상욱
Organometallics, 2006
A detailed investigation of light-harvesting efficiency of blue color emitting divergent iridium dendrimers with peripheral phenylcarbazole units
Yang-Jin Cho, Kyung-Ryang Wee, Ho-Jin Son, Dae Won Cho* and Sang Ook Kang*
PHYSICAL CHEMISTRY CHEMICAL PHYSICS, 2014
Efficient Light Harvesting and Energy Transfer in a Red Phosphorescent Iridium Dendrimer
Yang-Jin Cho, Seong Ahn Hong, Ho-Jin Son, Won-Sik Han, Dae Won Cho, and Sang Ook Kang
INORGANIC CHEMISTRY, 2014
Chemical conversions of salvianolic acid B by decoction in aqueous solution
Hyoung Jae Lee, Jeong-Yong Cho, Jae-Hak Moon
FITOTERAPIA, 2012
Photodynamic Behavior of Heteroleptic Ir(III) Complexes with Carbazole-Functionalized Dendrons Associated with Efficient Electron Transfer Processes
Ah-Reum Hwang, Won-Sik Han, Kyung-Ryang Wee, Hyun Young Kim, Dae Won Cho, Byoung Koun Min, Suk Woo N
Journal of Physical Chemistry C, 2012
Cycloaliphatic Epoxy Oligosiloxane-Derived Hybrid Materials for a High-Refractive Index LED Encapsulant
양승철, 김준수, 진정호, 곽승연, 배병수
JOURNAL OF MATERIALS CHEMISTRY, 2011
High performance organic-inorganic hybrid barrier coating for encapsulation of OLEDs
정경호, 배준영, 박수진, 유승협, 배병수
JOURNAL OF MATERIALS CHEMISTRY, 2011
Novel Ionic Iodide-Siloxane Hybrid Electrolyte for Dye-Sensitized Solar Cells
정경호, 배준영, 윤호경, 강만구, 배병수
ACS Applied Materials & Interfaces, 2010
제주도 우도 부근의 홍조단괴를 이용한 고수온과 단괴 성장률 추정: 고환경 복원에 대한 예비 연구 결과
허남국, 우경식, 홍완
지질학회지, 2011
Thermo-Mechanical/Thermal Properties of Photo-Cationic Polymerized Cyclo-Aliphatic Epoxy Hybrid Materials
양승철, 진정호, 곽승연, 배병수
MACROMOLECULAR RESEARCH, 2011
Fabrication of a High Thermal-Stable Methacrylate-Silicate Hybrid Nanocomposite Hydrolytic Vs. Non-hydrolytic Sol-Gel Synthesis of Methacryl-oligosiloxanes
진정호, 양승철, 배병수
JOURNAL OF SOL-GEL SCIENCE AND TECHNOLOGY, 2012
High Performance Encapsulant for Light-Emitting Diodes (LEDs) by a Sol-Gel derived Hydrogen Siloxane Hybrid
김준수, 양승철, 곽승연, 최용원, 백경욱, 배병수
JOURNAL OF MATERIALS CHEMISTRY, 2012
Panax ginseng improves survival and sperm quality in guinea pigs exposed to 2,3,7,8-tetrachlorodibenzo-p-dioxin
SEOCK-YEON HWANG, WUN-JAE KIM, JAE-JOON WEE, JONG-SOON CHOI and SI-KWAN KIM
British Journal of Urology International, 2004
마이크로파를 이용한 간담도계 영상 방사성의약품 99mTc-Mebrofenin의 합성
권희정, 장승호, 박상현, 신병철
Journal of the Korean Chemical Society, 2005
Synthesis of hyperbranched carbosiloxane macromolecule with triallyloxysilane and applications to the dndritic core.
김정균, 김효정
Comptes Rendus Chime, 2004
Synthetic, Electrochemical, and Theoretical Studies of Tetrairidium Clusters Bearing Mono- and Bis[60]fullerene Ligands
BoKeunPark,GaehangLee,KyoungHoonKim,HongkyuKang,ChangYeonLee,JaehooJung,Young-KyuHan,Joon T. Park
Journal of American Chemical Society, 2006
Syntheses, Structures, and Electrochemical Properties of Os3(CO)9-n(CNCH2Ph)n(í3-è2:è2:è2-C60) (n = 2-4)
Chang Yeon Lee, Bo Keun Park, Jung Hee Yoon, Chang Seop Hong,Joon T. Park
Organometallics, 2006
Hydrogeochemistry and environmental isotopes of ground water in Jeju volcanic island, Korea: Implications for nitrate contamination
Dong-Chan Koh, Ho-Wan Chang, Kwang-Sik Lee, Kyung-Seok Ko, Yongje Kim, Won-Bae Park
hydrogeochemical processes, 2005
Biochemical Charaterization of Acharan Sulfate Binding Proteins Associated with Anticoagulation in Human Plasma
이인선
서울대학교 대학원, 2004
Facile synthesis of Fréchet type dendritic benzyl azides and triazole dendrimer via click chemistry using tripodal core.
Jae Wook Lee
Bull.KoreanChem.Soc, 2005
Convergent Synthesis of Symmetrical and Unsymmetrical PAMAM Dendrimers.
Jae Wook Lee
Macromolecules., 2006
Convergent Synthesis of PAMAM-like Dendrimers from Azide-functionalized PAMAM Dendrons
Jae Wook Lee
Bull. Korean Chem. Soc., 2006
Convergent synthesis of PAMAM dendrimers using click chemistry of azide-functionalized PAMAM dendrons
Jae Wook Lee
Tetrahedron, 2006
Synthesis of Fréchet type dendritic benzyl propargyl ether and Fréchet type triazole dendrimer
Jae Wook Lee
Tetrahedron, 2006
Synthesis of Symmetric and Unsymmetric Triazole Dendrimers via Dipolar Cycloaddition Reaction
Jae Wook Lee
Synthesis, 2006
Cytotoxic Activity of Aminoderivatized Cationic Chitosan Derivatives
이정걸, 임현수, 김정혜
Bioorganic and Medical Chemistry Letters, 2002
L-Glutamate Enhances the Expression of Thermus Maltogenec Amylase in Escherichia coli
이정걸, 정형무, 박관화, 김상용
Biotechnology progress letter, 2003
Diels-alder reaction of anthracene on carbosilane dendrimer
김정균, 임경인, 송정근
Journal of organometallic chemistry, 2005
Preparation and Diels-Alder reaction of carbosilane dendrimer with conjugated diene
김정균, 김혜선, 박경래
Journal of organometallic chemistry, 2005
Synthesis of farnesyl-terminated carbosilane dendrimer
김정균, 김혜선
Journal of synthetic organic chemistry, 2005
Dendrimer 표면에서의 diels-alder 반응과 terpyridine 착물의 합성 연구
임경인
동아대학교, 2004
Siloxane dendrimer의 기능화 반응에 관한 연구
전혜영
동아대학교, 2004
다중결합성 작용기를 가지는 carbosilane dendrimer의 합성과 반응성
김혜선
동아대학교, 2004
다중결합을 갖는 Carbosilane Dendrimer의 합성과 반응성에 관한 연구
서원주
동아대학교, 2004
Silane Arborols; (XV): A Dendritic Carbosilane Based on Siloxane Tetramer
Chungkyun Kim, Aejeong Kwon
Synthesis, 1998
Synthesis of Carbosilane Dendrimer Based on Tetrakis(phenylethynyl)silane
Chungkyun Kim, Moon Kim
J. Organomet. Chem., 1998
Preparation and identification of dendritic carbosilanes containing allyloxy groups derived from 2,4,6,8-tetramethyl-2,4,6,8- tetravinylcyclotetrasiloxane (Me(CH2=CH)SiO)4 and 1,2-bis(triallyloxysilyl)ethane ((CH2=CHCH2O)3SiCH2)2
Chungkyun.Kim, Younsook. Jeong, Inkyung Jung
J. Organomet. Chem., 1998
Preparation of Dendritic Carbosilanes with Peripheral Ethynyldicobalt Hexacarbonyl Tetrahedrane C2CO2
Chyngkyun Kim, Inkyung Jung
Inorg. Chem. Commun., 1998
신 이식 후 재발된 국소성 분절성 사구체 경화증 환자에서 Circulating Factor(s)에 관한 연구
황의원, 김승일, 김은나, 임현진, 변정득, 박형근, 이은영, 양동호, 홍세용
대한신장학회지, 2001
End-capped dendric ethynylsilanes with ferrocene, amine and pyridine derivatives
김정균, 정인경, 송정근, 구본원
main group metal chemistry, 2002
Dendritic carbosilanes containing hydroxy groups on the periphery
Chungkyun Kim, Sungmo Son, Bohyun Kim
Journal of Organometallic Chemistry, 1999
Preparation of dendritic carbosilanes containing ethynyl groups and dicobalt hexacarbonyl clusters on the periphery
Chungkyun Kim, Inkyung Jung
Journal of Organometallic Chemistry, 1999
Preparation of dendritic carbosilanes containing propagyloxy groups
Chungkyun Kim, Jeongha Park
Synthesis, 1999
신 이식후 재발된 국소성 분절성 사구체 경화증 환자에서 circulating factor에 관한 연구
황의원, 김승일, 김은나, 임현진, 변정득, 박형근, 이은영, 양동호, 홍세용
대한 신장학회지, 2001
Cecropin D-like Antibacterial Peptides from the Sphingid moth, Agrius convolvuli
이인희, 장근영, 최충식, 김학렬
Archives of Insect Biochemistry and Physiology, 1999
Detection and characterization of the Gloeosporium gloeosporiodes growth inhibitory compound iturin A from Bacillus subtilis strain KS03
S.J. Cho, S.K. Lee, B.J. Cha, Y.H. Kim, K.S. Shin
FEMS Microbiol. Lett., 2003
End-capped carbosiloxane dendrimers with benzoxazole, quinoline and pyrone derivatives
김정균, 박은미
Journal of Polymer Science. Part A: Polymer Chemistry, 2001
End-capped AB3-type hyerbranched carbosilane macromolecules
김정균, 김효정
Journal of Polymer Science. Part A: Polymer Chemistry, 2001
2,2:6,2-Terpyridine and bis(2,2:6,2-terpyridine)ruthenium (II) complex on the dendritic periphery
김정균, 김효정
J. Organometallic Chemistry, 2003
The role of alpha-amino group of the N-terminal serine of beta subunit for enzyme catalysis and autoproteolytic activation of glutaryl 7-aminocephalosporanic acid acylase
이영식, 김형욱, 박성수
Journal of Biological Chemistry, 2000
Termination of Carbosilane Dendrimers Based on Hexaallylethylenedisilare as Core Molecule
Chyngkyun Kim, Younsook Jeong
Main Group Metal Chem, 1998
Purification and Characterization of antibacterial Peptides, Spodopsin Ia and Ib Induced in the Larval Haemolymph of the Common Cutworm, Spodoptera litura
Chung Sik Choi, Sung Moon Yoe, Eung Seok Kim, Kwon Seok Chae, Hak R. Kim
Korean J. Biol Sci., 1997
Purification, Characterization and cDNA Sequence of Apolipophorin-III from the Common Cutworm, Spodoptera litura.
Eung Seok Kim
고려대학교, 1997
담배거세미나방(Spodoptera litura)으로부터 항균단백질 spodopsin Ia, Ib의 정제 및 cDNA sequences
최충식
고려대학교, 1996
A cyclohexanonyl bromophenol from the red alga Symphyocladia latiuscula
Jae Sue Choi, Hye Jin Park, Hyun Ah Jung, Hae Young Chung, Jee H. Jung, Won Chul Choi
Journal of Natural Products, 2000
Revealing urologic diseases by proteomic techniques
Seung-won Lee, Kum-Il Lee, Jin Young Kim
Journal of Chromatography B, 2005
Proteome analysis of metabolically engineered Escherichia coli producing poly(3-hydroxybutyrate)
MEE-JUNG HAN, SANG SUN YOON, AND SANG YUP LEE
Journal of Bacteriology, 2001
Combined transcriptome and proteome analysis of Escherichia coli during high cell density culture
Sung Ho Yoon, Mee-Jung Han, Sang Yup Lee, Ki Jun Jeong, and Jong-Shin Yoo
Biotechnology and Bioengineering, 2003
Engineering Escherichia coli for increased production of serine-rich proteins based on proteome profiling
Mee-Jung Han, Ki Jun Jeong, Jong-Shin Yoo, and Sang Yup Lee
Applied and Environmental Microbiology, 2003
Synthesis of Symmetrical and Unsymmetrical PAMAM Dendrimers by Fusion between Azide- and Alkyne-Functionalized PAMAM Dendrons
이재욱(Jae Wook Lee)
Bioconjugate Chemistry, 2007
Functional proteomic study reveals that N-acetylglucosaminyltransferase V reinforces the invasive/metastatic potential of colon cancer through aberrant glycosylation on TIMP-1
Yong-Sam Kim, Soo Young Hwang, Hye-Yeon Kang, Hosung Sohn, Sejeong Oh, Jin-Young Kim, Jong Shin Yoo,
Molecular & Cellular Proteomics, 2007
\"[Os3(CO)6(PMe3)3][μ3-η2:η2:η2-C60][Re3(μ-H)3(CO)9]: One Fullerene[60] Coordinated to Two Different Trimetallic Clusters\"
Park, B. K.; Lee, C. Y.; Jung, J.; Jung, H. Y.; Han, Y. -K.; Hong, C. S.; Park, J. T.
Angew. Chem. Int. Ed., 2007
Lectin precipitation using phytohemagglutinin-L4 coupled to avidin-agarose for serological biomarker discovery in colorectal cancer
고정헌
PROTEOMICS, 2008
Effect of 2,3,7,8-tetrachlorodibenzo-p-dioxin on testicular spermatogenesis-related panels and serum sex hormone levels in rats
Jong-Soon Choi, Il-Woong Kim, Seock-Yeon Hwang, Bong-Jeong Shin and Si-Kwan Kim
British Journal of Urology International, 2007
Functional Proteomics Study Reveals That N-acetylglucosaminyltransferase V Reinforces the Invasive/Metastatic Potential of Colon Cancer through Aberrant Glycosylation on Tissue Inhibitor of Metalloproteinase-1*
고정헌
Research, 2008
Association of CD38 with Nonmuscle Myosin Heavy Chain IIA and LCK Is Essential for the Internalization and Activation of CD38
So-young,Kwan-Hyun Park,Tae-Sik Nam,Sang-Jin Kim,Hyuntae Kim,Mie-Jae Im,and Uh-Hyun Kim
JOURNAL OF BIOLOGICAL CHEMISTRY, 2007
Metacercarial proteins interacting with WD40-repeat protein of Clonorchis sinensis
Pyo Yun Cho, Tae Im Kim, Shunyu Li, Sung-Jong Hong, Min-Ho Choi, Sung-Tae Hong, and Yong Je Chung
Korean Journal of Parasitology, 2007
Bacterial production and structure-functional validation of a recombinant antigen-binding fragment (Fab) of an anti-cancer therapeutic antibody targeting epidermal growth factor receptor
김지훈, 심대원, 박동선, 정태근, 이성환, 오태흔, 하종렬, 석승현, 서민덕, 강호철, 김영필, 원형식
APPLIED MICROBIOLOGY AND BIOTECHNOLOGY, 2016
Anti-Inflammatory Action of an Antimicrobial Model Peptide That Suppresses the TRIF-Dependent Signaling Pathway via Inhibition of Toll-Like Receptor 4 Endocytosis in Lipopolysaccharide-Stimulated Macrophages
심도완, 허강혁, 김영규, 심은정, 강태봉, 최재완, 심대원, 정선희, 이승홍, 방정규, 원형식, 이광호
PLoS One, 2015
Recyclable scavengers for photo-cyclopropanation via an in situ crystallization process
이해리, 최은경, 노태환, 정옥상*
DALTON TRANSACTIONS, 2016
Bacterial production and structure-functional validation of a recombinant antigen-binding fragment (Fab) of an anti-cancer therapeutic antibody targeting epidermal growth factor receptor
김지훈, 심대원, 박동선, 정태근, 이성환, 오태훈, 하종렬, 석승현, 서민덕, 강호철, 김영필, 원형식
APPLIED MICROBIOLOGY AND BIOTECHNOLOGY, 2016
Development of a theranostic convergence bioradiopharmaceutical for immuno-PET based radioimmunotherapy of L1CAM in cholangiocarcinoma model
In HoSong, Mun SikJeong, Hyo JeongHong, Jong IlShin, Yong SerkPark, Sang KeunWoo, Byung SeokMoon, Kwang IlKim, Yong JinLee, Joo HyunKang, Tae SupLee,
CLINICAL CANCER RESEARCH, 2019
Immuno-PET imaging based radioimmunotherapy in head and neck squamous cell carcinoma model
In HoSong, YounNoh, JunhyeKwon, Jae HoJung, Byung ChulLee, Kwang IlKim, Yong JinLee, Joo HyunKang, Chae SeoRhee, Chul HeeLee, Tae SupLee, Ik JoonChoi,
Oncotarget, 2017
Immuno-PET imaging and radioimmunotherapy of 64Cu-177Lu-Labeled Anti-EGFR antibody in esophageal squamous cell carcinoma model
In HoSong, Tae SupLee, Yong SerkPark, Jin SookLee, Byung ChulLee, Byung SeokMoon, Gwang IlAn, Hae WonLee, Kwang IlKim, Yong JinLee, Joo HyunKang, Sang MooLim,
JOURNAL OF NUCLEAR MEDICINE, 2016
Development of a novel short 12-meric papiliocin-derived peptide that is effective against Gramnegative sepsis
Jieun Kim, Binu Jacob, Mihee Jang, Chulhee Kwak, Yeongjoon Lee, Kkabi Son, Sujin Lee, In Duk Jung, Myeong Seon Jeong, Seung-Hae Kwon and Yangmee Kim
Scientific Reports, 2019

이용자 리뷰


챗봇 켜기