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보유센터 및 부서	오창센터 바이오융합연구부
장비담당자	한은희  김정아
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Spec 및 활용분야

원리 및 특징	Laser를 광원으로 사용하여 시료를 광학적 절편 형태로 관찰할 수 있는 형광현미경의 일종으로 시료를 물리적으로 변형시키지 않고 3차원적인 영상을 만들어낼 수 있기 때문에 살아있는 세포의 실시간 분석과 세포내 소기관 또는 신호전달물질의 시간적 변화를 관찰할 수 있는 장비이다.
구성 및 성능	○ Lasers 1. Multi-Argon laser 458/488/514 nm-적용가능 형광물질: CFP, GFP, FITC, Alexa 488, Cy2, YFP, Fluo-3… 2. UV Diode 405nm-적용가능 형광물질: DAPI, Hoechest, BFP, PA-GFP, KAEDE… 3. HeNe laser 543nm-적용가능 형광물질 : Rhodamine, Cy3, Alexa 546, Texas Red, RFP, DsRed… 4. HeNe laser 633nm-적용가능 형광물질: Cy5, Alexa 633… ○ PMT detector for fluorescence and transmitted/DIC light ○ Transmitted light and X-Cite fluorescence Illuminator. ○ Two galvanometric scanning confocal heads (for DIC/Phase Contrast and Fluorescence imaging). ○ Motorized stage 130x85 for x,y,z movement. ○ Master pinhole. ○ Optics: EC Plan-Neofluar 10x/0.30 WD=5.2, Plan-Apochromat 20x/0.8 WD=0.55; Plan-Apochromat 40x/0.95 Corr WD=0.25; EC Plan-Neofluar 40x/1.3 DIC WD=0.21; Plan-Apochromat 63x/1.40 Oil DIC, 100x/1.4 oil Plan-Apochromat DIC ○ AxioCam MRm Rev.3 camera for regular transmitted/fluorescence widefield imaging. ○ Definite Focus system for longer term live cells imaging. ○ Anti-vibration table. ○ Zeiss ZEN 2009 software.0
활용분야	○세포 이미징 및 형광 단백질 발현 정량 분석 : 생명공학 및 의약학 분야 (세포, 조직) 시료

Bioinspired tuning of glycol chitosan for 3D cell culture

Myeong Ok Cho, Zhengzheng Li, Hye-Eun Shim, Sun-Woong Kang et al

NPG Asia Materials, 2016

Synthesis and characterization of a new photo-crosslinkable glycolchitosan thermogel for biomedical applications

Ik Sung Cho, Myeong Ok Cho, Zhengzheng Li, Md Nurunnabi, Sung Young Park, Sun-Woong Kang, Kang Moo Huh

CARBOHYDRATE POLYMERS, 2015

Vitamin D3 Induces Autophagy in Human Monocytes/Macrophages via Cathelicidin

Jae-Min Yuk,1,2,6 Dong-Min Shin,1,2,6 Hye-Mi Lee,1,2 Chul-Su Yang,1,2 Hyo Sun Jin,1,2 Kwang-Kyu Kim,

Cell Host & Microbe, 2009

Host cell autophagy activated by antibiotics is required for their effective antimycobacterial drug action.

Kim JJ1, Lee HM, Shin DM, Kim W, Yuk JM, Jin HS, Lee SH, Cha GH, Kim JM, Lee ZW, Shin SJ, Guang-Ho C

Cell Host & Microbe, 2012

Mycobacterium tuberculosis eis regulates autophagy, inflammation, and cell death through redox-dependent signaling.

Dong-Min Shin1,2., Bo-Young Jeon3., Hye-Mi Lee1,2, Hyo Sun Jin1,2, Jae-Min Yuk1,2, Chang-Hwa Song1,S

PLoS Pathogens, 2010

Nanoparticles up-regulate tumor necrosis factor-! and CXCL8 via reactive oxygen species and mitogen-activated protein kinase activation

Hye-Mi Lee, Dong-Min Shin, Hwan-Moon Song, Jae-Min Yuk, Zee-Won Lee, Sang-Hee Lee, Song Mei Hwang, Jin-Man Kim, Chang-Soo Lee, Eun-Kyeong Jo

TOXICOLOGY AND APPLIED PHARMACOLOGY, 2009

NADPH Oxidase 2 Interaction with TLR2 Is Required for Efficient Innate Immune Responses to Mycobacteria via Cathelicidin Expression

Chul-Su Yang, Dong-Min Shin, Ki-Hye Kim, Zee-Won Lee, Chul-Ho Lee, Sung Goo Park, Yun Soo Bae and Eun-Kyeong Jo

JOURNAL OF IMMUNOLOGY, 2009

Micropatterns of spores displaying heterologous proteins

Tae Jung Park, Kyung-Bok Lee, Seok Jae Lee, Jong Pil Park, Zee-Won Lee, Sang Yup Lee, Insung S. Choi

J. Am. Chem. Soc., 2004

Protein nanopatterns and biosensors using gold binding polypeptide as a fusion partner

Tae Jung Park, Sang Yup Lee, Seok Jae Lee, Jong Pil Park, Kwang Suk Yang, Kyung-Bok Lee, Sungho Ko,

Anal. Chem., 2006

Pattern Generation of Biological Ligands on a Biodegradable Poly(glycolic acid) Film.

Lee, K.-B.; Kim, D. J.; Lee, Z.-W.; Woo, S. I.; Choi, I. S.

Langmuir, 2004

Microcontact Printing of Biotin for Selective Immobilization of Streptavidin-Fused Proteins and SPR Analysis.

Park, J. P.; Lee, S. J.; Park, T. J.; Lee, K.-B.; Choi, I. S.; Lee, S. Y.; Kim, M.-G.; Chung, B. H.

Biotechnology and Bioprocess Engineering, 2004

Micropatterens of Spores Displaying Heterologous Proteins.

Park, T. J.; Lee, K.-B.; Lee, S. J.; Park, J. P.; Lee, Z.-W.; Lee. S. Y.; Choi, I. S.

Journal of American Chemical Society, 2004

Transcriptional regulation of the human transferrin gene by GADD153 in hepatoma cells.

You KR, Liu MJ, Han XJ, Lee ZW, Kim DG.

Hepatology, 2003

Over-expression of the ribosomal protein L36a gene is associated with cellular proliferation in hepatocellular carcinoma.

Kim JH, You KR, Kim IH, Cho BH, Kim CY, Kim DG.

Hepatology, 2004

Activation of Ras Up-regulates Pro-apoptotic BNIP3 in Nitric Oxide-induced Cell Death

Hyun-Jung An, Oky Maeng, Kyoung-Hee Kang, Jie-Oh Lee, Young-Sang Kim, Sang-Gi Paik,Hayyoung Lee

The journal of biology chemistry, 2006

Single Cell Array of Biotinylated Cells Using Surface Functionalization and Microcontact printing

Lee, Z.-W.; Lee, K.-B.; Hong, J. H.; Kim, J.-H.; Choi, I.; Choi, I. S.

Chem. Lett., 2005

Photolithographical Immobilization of Biomolecules onto Non-Biofouling Surfaces

Lee, Z.-W.; Lee, K.-B.; Hong, J.-H.; Kim, J.-H.; Cheong, C.; Choi, I. S.

Bull. Korean Chem. Soc., 2005

Micropatterning Proteins on Polyhydroxyalkanoate Substrates by Using the Substrate Binding Domain as a Fusion Partner

Park, J. P.; Lee, K.-B.; Lee, S. J.; Park, T. J.; Kim, M. G.; Chung, B. H.; Lee, Z.-W.; Choi, I. S.;

Biotechnol. Bioeng., 2005

Protective Role of Tissue Transglutaminase in the Cell Death Induced by TNF-α in SH-SY5Y Neuroblastoma Cells.

Soo-Mi Kweon, Zee-Won Lee, Sun-Ju Yi, Young-Myeong Kim, Jeong-A Han, Sang-Gi Paik and Kwon-Soo Ha

Journal of Biochemistry and Molecular Biology, 2004

Susceptibility of cholangiocarcinoma cells to parthenolide-induced apoptosis.

Kim JH, Liu L, Lee SO, Kim YT, You KR, Kim DG.

Cancer Res., 2005

Involvement of GADD153 and cardiac ankyrin repeat protein in hypoxia-induced apoptosis of H9c2 cells.

Han XJ, Chae JK, Lee MJ, You KR, Lee BH, Kim DG.

J Biol Chem, 2005

Identification of the genes involved in enhanced fenretinide-induced apoptosis by parthenolide in human hepatoma cells.

Park JH, Liu L, Kim IH, Kim JH, You KR, Kim DG.

Cancer Res., 2005

PINOID Positively Regulates Auxin Efflux in Arabidopsis Root Hair Cells and Tobacco Cells

Sang Ho Lee and Hyung-Taeg Cho

The Plant Cell, 2006

Thioredoxin modulates activator protein 1 (AP-1) activity and p27Kip1 degradation through direct interaction with Jab1

Chae Young Hwang1and Ki-Sun Kwon1

oncogene, 2004

PINOID Positively Regulates Auxin Efflux in Arabidopsis Root Hair Cells and Tobacco Cells

Sang Ho Lee and Hyung-Taeg Cho

The Plant Cell, 2006

LPS-induced CD53 expression : a protection mechanism against oxidative and radition stress

Kim TR, Yoon JH, Kim YC, Yook YH, Kim IG, Kim YS, Lee H, Paik SG.

Molecules and Cells, 2003

Cytosolic NADP(+)-dependent isocitrate dehydrogenase protects macrophages from LPS-induced nitric oxide and reactive oxygen species.

Maeng O, Kim YC, Shin HJ, Lee JO, Huh TL, Kang KI, Kim YS, Paik SG, Lee H.

Biochem Biophys Res Commun, 2004

Nitric oxide induces BNIP3 expression that causes cell death in macrophages.

Yook YH, Kang KH, Maeng O, Kim TR, Lee JO, Kang KI, Kim YS, Paik SG, Lee H.

Biochemical and Biophysical Research Communnications, 2004

Spatial Control over Chemical Functionalization of Biodegradable Poly(glycolic acid) (PGA) Sutures: Bulk vs. Surface Functionalization

Lee, K.-B.; Lee, Y.-W.; Kim, D. J.; Lee, S. M.; Woo, S. I.; Kim, Y.-G.; Choi, I. S.

Bull. Korean Chem. Soc., 2003

Functional Conservation of a Root Hair Cell-Specific cis-Element in Angiosperms with Different Root Hair Distribution Patterns

김동욱, 이상호, 최상봉, 원수경, 허윤경, 조미숙, 박연일, 조형택

The Plant Cell, 2006

A novel zinc finger protein that inhibits osteoclastogenesis and the function of tumor necrosis factor feceptor-associated factor 6

신진나,김인준,이정섭,고규영,이장희,김홍희

The Journal of Biological Chemistry, 2002

Surface Modification of Poly(glycolic acid) (PGA) for Biomedical Applications

Lee, K.-B.; Yoon, K. R.; Woo, S. I.; Choi, I. S.

J. Pharm. Sci., 2003

Formation of Thermoresponsive Poly(N-isopropylacrylamide)/Dextran Particles by Atom Transfer Radical Polymerization

Kim, D. J.; Heo, J.-y.; Choi, I. S.

Macromol. Rapid Commun., 2003

Patterning Si/SiO2 by Using Surface Functionalization and Microcontact Printing with a Polymeric Ink

Lee, K.-B.; Kim, D. J.; Yoon, K. R.; Kim, Y.; Choi, I. S.

Korean J. Chem. Eng., 2003

Reactivity of Vinyl-Terminated Self-Assembled Monolayers on Gold: Olefin Cross-Metathesis Reactions

Lee, J. K.; Lee, K.-B.; Kim, D. J.; Choi, I. S.

Langmuir, 2003

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eahajasjrja, 1999

Agonist-specific differential changes of cellular signal transduction pathways in senescent human diploid fibroblasts

Yeo, E.-J., Jang, I.-S., Lim, H.-K., Ha, K.-S., & Park, S. C.

Exp. Gerontol., 2002

Signaling by phosphatidylcholine-hydrolyzing phospholipase D

Ha, K.S.

Saengwhahak Nyusu, 1994

Rho Family GTP-binding Protein의 조절과 기능

Kim, J.H. and Ha, K.-S.

분자생물학뉴스, 1996

Colchicine activates actin polymerization by microtubule depolymerization

Hyo Il Jung, Incheol Shin, Young Mok Park, Ke Won Kang, and Kwon-Soo Ha

Mol. Cells, 1997

Phospholipase D is not involved in RhoA-mediated activation of stress fiber formation

Leem, S.H., Shin, I.C., Kweon, S.M., Kim, S.I., Kim, J.H., and Ha, K.S.

J. Biochem. Mol. Biol., 1997

Principle and applications of laser scanning confocal microscope

Ha, K.S., and Lee, Z.W.

Ajou Med., 1997

Rac GTPase is essential for EGF-induced mitogenesis

Kim, B.C., Yi, J.Y., Yi, S.J., Shin, I.C., Ha, K.S., Jhun, B.H., Hwang, S.B., and Kim, J.H.

Mol. Cells, 1998

Measurement of nuclear Ca2+ using confocal microscope

Ha, K.S., and Lee, Z.W.

Curr. Cell Biol., 1998

Lysophosphatidic acid increases intracellular H2O2 by phospholipase D and RhoA in Rat-2 fibroblasts

Shin, I., Kweon, S.-M., Lee, Z.-W., Kim, S. I., Joe, C. O., Kim, J.-H., Park, Y. M., and Ha, K.-S

Mol. Cells, 1999

The analysis of methylenetetrahydrofolate reductase mutation in resurrent spontaneous abortion associated with hyperhomocysteinemia

Yoon Sung Nam, Jong Soon Choi, Kwon-Soo Ha, Zee-Won Lee, & Do Yeon Oh

Kor. J. Fertility & Sterility, 1999

Fibrin stimulates microfilament reorganization and IL-1βproduction in human monocytic THP-1 cells

Lee, M.E., Kweon, S.M., Ha, K.S. and Nham, S.U.

Mol. Cells, 2001

Principle and biological applications of protein chip systems

Ha, K.S.

Exp. Mol. Med., 2001

NYP distribution in diencephalon of developing chick

Lee, M.-Y., Park, I.-K., Lee, K.-Y., Kwon, H.-J., Park, M.-S., Lee, K.-I., Ha, K.-S., Kim, W.-S.,

대한수의학회지, 2002

Immunohistochemical localization of nerve growth factor, glial fibrillary acidic protein & ciliary neurotrophic factor in the forebrain of the developing mongolian gerbil

Park, I.-K., Lee, K.-Y., Kwon, H.-J., Park, M.-S., Lee, M.-Y., Jeong Y.-G., Lee, C.-H., Ha, K.-S

대한수의학회지, 2002

Immunohistochemical localization of nerve growth factor, glial fibrillary acidic protein & ciliary neurotrophic factor in mesenceplalon, rhombencephalon, & spinal cord of developing mongolian gerbil

Park, I.K., Lee, K.Y., Song, C.W., Kwon, H.J., Park, M.S., Lee, M.Y., Lee, K.J., Jeong, Y.G., Lee

J. Vet. Sci., 2002

he ring-H2 finger motif of CKBBP1/SAG is necessary for interaction with protein kinase CKII & optimal cell proliferation

Kim, Y-S., Ha, K.-S., Kim, Y.-H., & Bae, Y.-S.

J. Biochem. Mol. Biol., 2002

Isolation and characterization of guemerin, a new human leukocyte elastase inhibitor from Hirudo nipponia

Jung, H.I., Kim, S.I., Ha, K.S., Joe, C.O., and Kang, K.W.

J. Biol. Chem., 1995

Actin filaments in mature guard cells are radially distributed and involved in stomatal movement

Kim, M.J., Hepler, P.K., Eun, S.O., Ha, K.S., and Lee, Y.S.

Plant Physiol., 1995

Inhibition of the phosphorylation of a myristoylated alanine-rich C kinase substrate (MARCKS) by methyl methanesulfonate in cultured NIH3T3 cells

Shin, I., Kam, Y.S., Ha, K.S., Kang, K.W., and Joe, C.O.

Mut. Res., 1996

Two hevein homologs isolated from the seed of Pharbitis nil L. exhibit potent anti-fungal activity

Koo, J.C., Lee, S.Y., Chun, H.J., Cheong, Y.H., Kawabata, S., Miyagi, M., Ha, K.S., & Cho, M.J.

Biochem. Biophys. Acta, 1998

Phosphatidic acid-induced elevation of intracellular Ca2+ is mediated by RhoA and H2O2 in Rat-2 fibroblasts

Lee, Z.W., Kweon, S.M., Kim, B.C., Leem, S.H., Shin, I., Kim, J.H.., and Ha, K.S.

J. Biol. Chem., 1998

Evidence for role of phospholipase A2 in phosphatidic acid-induced signaling to c-fos serum response element activation

Kim, B.C., Ha, K.S., Park, J.B., and Kim, J.H.

Biochem. Biophys. Res. Commun., 1998

Arachidonic acid induces the activation of the stress-activated protein kinase, membrane ruffling and H2O2 production via a small GTPase Rac1.

hin, E.A., Kim, K.H., Han, S.I., Ha, K.-S., Kim, J.-H., Kang, K.I., Kim, H.D., and Kang, H.S.

FEBS Lett., 1999

Roles of RhoA and phospholipase A2 in the elevation of intracellular H2O2 by transforming growth factor-β in Swiss 3T3 fibroblasts

Koo, H.Y., Shin, I., Lee, Z.W., Lee, S.H., Lee, C.H., Kang, H.S., and Ha, K.S.

Cellular Signaling, 1999

Silica-induced generation of reactive oxygen species in Rat-2 fibroblast: role in activation of mitogen-activated protein kinase

Cho, Y-J., S, M.-S., Kim, J. K., Lim, Y., Chae, G., Ha, K.-S., & Lee, K.-H.

Biochem. Biophys. Res. Commun., 1999

Hydrogen peroxide activates p70S6K signaling pathway

Bae, G.-U., Seo, D.-W., Kwon, H.-K., Lee, H.-Y., Hong, S., Lee, Z.-W., Ha, K.-S., Lee, H.-W. & Ha

J. Biol. Chem., 1999

The essential role of H2O2 in the regulation of intracellular Ca2+ by epidermal growth factor in Rat-2 fibroblasts

Lee, Z.-W., Kweon, S.-M., Kim, S.-J., Kim, J.-H., Cheong, C., Park, Y.-M., & Ha, K.-S.

Cellular Signaling, 2000

Involvement of cytosolic phospholipase A2, and the subsequent release of arachidonic acid, in signaling by Rac for the generation of intracellular reactive oxygen species in Rat-2 fibroblasts

Woo, C.-H., Lee, Z.W., Kim, B.C., Ha, K.S., and Kim, J.H.

Biochem. J., 2000

The role of RhoA in the germinal vesicle breakdown of mouse oocytes

Cheon, Y.P., Kim, S.W., Kim, S.J., Yeom, Y.I., Cheong, C., and Ha, K.S.

Biochem. Biophys. Res. Commun., 2000

Effects of N-acetyl-L-cysteine and Glutathione on Antioxidant Status of Human Serum and 3T3 Fibroblasts

Hong SY, Yang JO, Lee EY, Lee ZW

Journal of Korean Medical Science, 2003

Requirement of hydrogen peroxide generation in TGF-β1 signal transduction in human lung fibroblast cells: Involvement of hydrogen peroxide and Ca2+ in TGF-β1-indiced IL-6 expression

Junn, E., Lee, K.N., Ju, H.R., Han, S.H., Im, J.Y., Kang, H.S., Lee, T.H., Bae, Y.S., Ha, K.S., L

J. Immonol., 2000

Heat shock-induced actin polymerization, SAPK/JNK activation, and heat-shock protein expression are mediated by genistein-sensitive tyrosine kinase(s) in K562 cells

Han, S.I., Ha, K.S., Kang, K.I., Kim, H.D., & Kang, H.S.

Cell Biol. Intl., 2000

The role of tissue transglutaminase in the germinal vesicle breakdown of mouse oocytes

Kim, S.W., Lee, Z.-W., Lee, C., Im, K.S. and Ha, K.-S.

Biochem. Biophys. Res. Commun., 2001

Involvement of phospholipase D in oxidative stress-induced necrosis of vascular smooth muscle cells

Shin, E.-Y., Min, D.S., Shin, J.-C., Shin, K.-S., Hyun, M.S., Ha, K.-S., Kim, H.S., Ahn, H.Y., &

FEBS Lett., 2001

Real-time measurement of intracellular reactive oxygen species using MitoTracker orange (CMH2TMRos)

Kweon, S.M., Kim, H.J., Lee, Z.W., Kim, S.J., Kim, S.I., Paik, S.K. and Ha, K.S.

Bioscience reports, 2001

Regulation of reactive oxygen species and stress fiber formation by calpeptin in Swiss 3T3 fibroblasts

Kim, S.J., Lee, Z.-W., Kweon, S.-M., Kim, S. and Ha, K.-S.

Cellular Signaling, 2002

Expression of wild-type & truncated myocilins in trabecular meshwork cells

Sohn, S., Hur, W., Joe, M.K., Kim, J.-H., Lee, Z.-W., Ha, K.S., & Kee, C.

Invest. Ophthalmol. Vis. Sci., 2002

Protective role Of Tissue Transglutaminase in the Cell Death Induced by TNF-α in SH-SY5Y Neuroblastoma Cells.

Kweon,S.-M., Lee,Z.-W., Yi,S.-J., Kim,Y.-M. Han,J.-A., Paik,S.-G., and Ha,K.-S.

J. Biochem. Mol. Biol, 2003

Activation of in situ Tissue Transglutaminase by Intracellular Reactive Oxygen Species.

Zee-Won Lee, Sang-Mo Kwon, sung-Woo Kim, Sun-Ju Yi, Young-Myeong Kim & Kwon-soo Ha

Biochem. Biophys. Res. Commun., 2003

Characterization of Surface Plasmon Resonance Wavelength by Changes of Protein Chips.

Jong Seol Yuk, Sun-Ju Yi, Hyeon Gon Lee, Young-Myung Kim, and Kwon-Soo Ha

Sensors & Actuators B, 2003

Layer-by-layer method for immobilization of protein molecules on biochip surface

Zhavnerko, G.K., Yi, S.J., Kweon, S.M. & Ha, K.S.

NATO Science Series, 2002

Effects of N-acetyl-L-cysteine and Glutathione on Antioxidant Status of Human Serum and 3T3 Fibroblasts

Hong SY, Yang JO, Lee EY, Lee ZW:

J Korean Med Sci, 2003

Rac GTPase Activity is Essential for EGF-Induced Mitogenesis in Rat-2 Fibroblasts Cells

B.C. Kim, J.Y. Yi, S.J.Yi, I. C. Shin, K. S. Ha., B. H. Jhun, S. B. Hwang, J. H. Kim

Mol. & Cells., 1998

Evidence for Role of Phospholipase A2 in Phosphatidic acid-induced Signaling to c-fos serum response element activation

Kim, B.C., Ha, K.S., Park, J.B.,J.H. Kim

Biochem. Biophy. Res. Comm., 1998

Phosphatidic Acid-induced Elevation of Intracellular Ca2+ is Mediated by RhoA and H2O2 in Rat-2 Fibroblasts

Lee, Z.W., Kweon, S.M., Kim, B.C., Leem, S.H., Shin, I.C., Kim, J.H., K.S. Ha

J. Biol. Chem., 1998

Phospholipase D is not Involved in Rho A-Mediated Activation of Stress Fiber Formation

Leem, S.H., Shin, i.C., Kwon, S.M., Kim, S.I. Kim, J.H., K.S. Ha

J. Biochem. Mol. Biol., 1997

In Vivo Synthesis of Diverse Metal Nanoparticles by Recombinant Escherichia coli

Tae Jung Park, Sang Yup Lee, Nam Su Heo, Tae Seok Seo

Angewandte Chemie International Edition, 2010

Microcontact printing of biotin for selective immobilization of streptavidin-fused proteins and SPR analysis

Jong Pil Park, Seok Jae Lee, Tae Jung Park, Kyung-Bok Lee, Insung S. Choi, Min-Gon Kim, Bong Hyun Ch

Biotechnol. Bioprocess Eng., 2004

Essential roles and applications of small heat shock proteins in the production of recombinant proteins in Escherichia coli

Mee-Jung Han, Si Jae Park, Tae Jung Park, and Sang Yup Lee

Biotechnol. Bioeng., 2004

Micropatterning proteins on polyhydroxyalkanoate substrates by using the substrate binding domain as a fusion partner

Jong Pil Park, Kyung-Bok Lee, Seok Jae Lee, Tae Jung Park, Min-Gon Kim, Bong Hyun Chung, Zee-Won Lee

Biotechnol. Bioeng., 2005

Micropatterning Proteins on Polyhydroxyalkanoate Substrates by Using the Substrate Binding Domain as a Fusion Partner

J.P. Park, K.-B. Lee, S.J. Lee, T.J. Park, M.G. Kim, B.H. Chung, Z.-W. Lee, I.S. Choi, S.Y. Lee

Biotechnol. Bioeng., 2005

Micropatterns of Spores Displaying Heterologous Proteins

T.J. Park, K.-B. Lee, S.J. Lee, J.P. Park, Z.-W. Lee, S.Y. Lee, I.S. Choi

JACS, 2004

P-Glycoprotein4 Displays Auxin Efflux Transporter-Like Action in Arabidopsis Root Hair Cells and Tobacco Cells

Misuk Cho, Sang Ho Lee, and Hyung-Taeg Cho

The Plant Cell, 2007

NF-Y-Dependent Cyclim B2 Expression in Colorectal Adenocarcinoma

Seon-Hwa Park, Gyung-Ran Yu, Woo-Ho Kim, Woo-Sung Moon

Clin Cancer Res, 2007

Identification of molecular markers for the oncogenic differentiation of hepatocellular carcinoma

Gyung-Ran Yu, Seong-Hun Kim, Seon-Hqa Park, Xiang-Dan cui, Dong-Yuan Xu, Dae-Ghon Kim

Experimental and Moleculer medicine, 2007

Identification of cystatin B as A Potential Serum Marker in Hepatocellular Carcinoma

Mi-Jin Lee, Gyung-Ran Yu, Seon-Hwa Park, Baik-Hwan Cho, Jong-Seong Ahn, Hae-Joon Park, Dae-Ghon Kim

Clin Cancer Res, 2007

Nanoscaling Laws of Magnetic Nanoparticles and Their Applicabilities in Biomedical Sciences

Young-wook Jun, Jung-wook Seo, Jinwoo Cheon

Accounts Chem. Res., 2008

Chemical Design of Nanoparticle Probes for High-Performance Magnetic Resonance Imaging

Young-wook Jun, Jae-Hyun Lee, Jinwoo Cheon

Angew. Chem. Int. Ed., 2008

Hybrid Nanoparticle Probe for Dual-Modality Positron Emission Tomography and Magnetic Resonance Imaging

Jin-sil Choi, Jeong Chan Park, Hyunsoo Nah, Seungtae Woo, Jieun Oh, Kyeong Min Kim, Jinwoo Cheon

Angew. Chem. Int. Ed., 2008

Two-Dimensional SnS2 Nanoplates with Extraordinary High Discharge Capacity for Lithium Ion Batteries

Jung-wook Seo, Jung-tak Jang, Seung-won Park, Chunjoong Kim, Byungwoo Park, Jinwoo Cheon

Adv. Mater., 2008

Dual Functional, Polymeric Self-Assembled Monolayers as a Facile Platform for Construction of Patterns of Biomolecules.

Park, S.; Lee, K.-B.; Choi, I. S.; Langer, R.; Jon, S.

Langmuir, 2007

Biospecific Anchoring and Spatially Confined Germination of Bacterial Spores in Non-Biofouling Microwells.

Lee, K.-B.; Jung, Y. H.; Lee, Z.-W.; K. S.; Choi, I. S.

Biomaterials, 2007

Selective Immobilization of Biomolecules onto an Activated Polymeric Adlayer.

Lee, B. S.; Park, S.; Lee, K.-B.; Jon, S.; Choi, I. S.

Biointerphases, 2007

Functionalization of PolyOligoethylene glycol Methacrylate Films on Gold and Si/SiO2 for Immobilization of Proteins and Cells- SPR and QCM Studies.

Lee, B. S.; Chi, Y. S.; Lee, K.-B.; Kim, Y.-G.; Choi, I. S.

Biomacromolecules, 2007

Association of CD38 with Nonmuscle Myosin Heavy Chain IIA and LCK Is Essential for the Internalization and Activation of CD38

So-young,Kwan-Hyun Park,Tae-Sik Nam,Sang-Jin Kim,Hyuntae Kim,Mie-Jae Im,and Uh-Hyun Kim

JOURNAL OF BIOLOGICAL CHEMISTRY, 2007

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