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지역	춘천센터
주소	(24341) 강원도 춘천시 강원대학길1 강원대학교 집현관 한국기초과학지원연구원
보유센터 및 부서	춘천센터 분석연구부
장비담당자	김상구
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Spec 및 활용분야

원리 및 특징	전계방출주사전자현미경(FE-SEM)은 시료의 표면, 단면 등을 고배율로 확대하여 morphology분석 및 구조분석 장비로써, 나노사이즈의 입자크기, 박막두께, 구조분석 및 EDS를 이용한 성분분석을 고배율로 확대하여 분석 가능하다.
구성 및 성능	○Electron Source - Thermal Schottky field emitter ○Resolution - Electron Beam 0.8nm @15kV ○Beam Stability 0.2%/h ○GEMINI Column Electrostatic and Magnetic Lens ○Detectors - High efficiency In-lens Secondary Electron detector - Everhart-Thornley Secondary Electron Detector - Variable Pressure Secondary Electron Detector
활용분야	○ 곤충, 식물, 꽃, 동물조직의 표면 분석 ○ E-Coil, Bacteria, Yeast, Diatom, Cell, Tissue, Pollen 등 다양한 생물 시료의 nano-scale 관찰 ○ Cosmetic, Food, 섬유, 약품 등의 표면 분석 ○ Geology, Ceramic, Cement 시료의 표면분석 ○ 반도체, 전기, 전자 분야의 시료 표면분석 ○ EDS를 이용한 시료의 정성, 정량 분석- 예약전 반드시 유선으로 SEM 담당자와 예약상담 - 예약시간 모두 분석료가 청구되오니, 시료수와 분석예상 시간을 고려하여 예약신청 - 분석시간은 시료 전처리, 시료 분석, 정리까지 포함된 시간. 분석은 10분 전에 종료되며, 시료에 따라 전처리 시간이 다르므로 사전에 상담하시어 미리 방문하여 준비가능

Redox-responsive alginate microsphere containing cystamine

Kyeongnan Kwon & Jin-Chul Kim

JOURNAL OF BIOMATERIALS SCIENCE-POLYMER EDITION, 2016

Osteoinductive silk fibrointitanium dioxidehydroxyapatite hybrid scaffold for bone tissue engineering

김정호,김동규,이옥주,주형우,이정민,문보미,박현정,김동욱,이준호,박찬흠

INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, 2015

Fabrication of duck’s feet collagen–silk hybrid biomaterial for tissue engineering

김수현,박혜상,이옥주,Janet Ren Chao,박현정,이정민,주형우,문보미,박예리,송정은,강길선,박찬흠

INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, 2015

Wound healing effect of electrospun silk fibroin nanomatrix in burn-model

주형우,이옥주,이정민,문보미,박현정,박예리,이민채,김수현,Janet Ren Chao,기창석,박찬흠

INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, 2015

Fabrication of 3D porous SFb-TCP hybrid scaffolds for bone tissue reconstruction

박현정,민경단,이민채,김수현,이옥주,주형우,문보미,이정민,박예리,김동욱,정주연,박찬흠

J Biomed Mater Res Part A, 2016

초음파와 동결/융해에 의한 실크/PVA 하이드로젤의 제조 및 특성 평가

이옥주·김정호·주형우·문보미·박현정·Faheem A. Sheikh·박찬흠

POLYMER-KOREA, 2013

실크 피브로인을 함유한 비출혈용 복합 지혈제 개발에 대한 연구

문보미,주형우,박현정,이정민,이옥주,박찬흠

Tissue Engineering and Regenerative Medicine, 2013

A novel approach to fabricate silk nanofibers containing hydroxyapatite nanoparticles using a three-way stopcock connector

Faheem A. Sheikh,주형우, 문보미,박현정,김정호,이옥주,박찬흠

Nanoscale Research Letters, 2013

Comparative study of morphological and histological changes between differently structured expanded polytetrafluoroethylene implants in an animal model

김지희,이정민,주형우,이준호,전아영,박찬흠

American Journal of Rhinology & Allergy, 2013

Fe-P: A New Class of Electroactive Catalyst for Oxygen Reduction Reaction

Kiran Pal Singh, Eun Jin Bae, and Jong-Sung Yu*

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2015

A new class of electroactive Fe- and P-functionalized graphene for oxygen reduction

Fatemeh Razmjooei, Kiran Pal Singh, Eun Jin Bae, and Jong-Sung Yu*

Journal of Materials Chemistry A, 2015

Fabrication and Characterization of Three-Dimensional Silk Fibroin Scaffolds Using a Mixture of SaltSucrose

Bo Mi Moon, Dong-Kyu Kim, Hyun Jung Park, Hyung Woo Ju, Ok Joo Lee, Jung-Ho Kim, Jung Min Lee, Joong

Macromolecular Research, 2014

3D electrospun silk fibroin nanofibers for fabrication of artificial skin

Faheem A. Sheikh, Hyung Woo Ju, Jung Min Lee, Bo Mi Moon, Hyun Jung Park, Ok Joo Lee, Jung-Ho Kim, D

Nanomedicine: Nanotechnology, Biology, and Medicine, 2015

Fabrication of 3D porous silk scaffolds by particulate (saltsucrose)leaching for bone tissue reconstruction

Hyun Jung Park, Ok Joo Lee, Min Chae Leea, Bo Mi Moon, Hyung Woo Ju,Jung min Lee, Jung-Ho Kim, Dong

International Journal of Biological Macromolecules, 2015

Three-layered scaffolds for artificial esophagus using poly(E-caprolactone) nanofibers and silk fibroin: An experimental study in a rat model

Eun-Jae Chung, Hyung Woo Ju, Hyun Jung Park, Chan Hum Park

J Biomed Mater Res Part A, 2015

Hypothetical cathepsin-like protein from Nematostella vectensis and its silicatein-like cathepsin mutant for biosilica production

기미란, 장의경, 백승필

PROCESS BIOCHEMISTRY, 2014

Local delivery of alendronate eluting chitosan scaffold can effectively increase osteoblast functions and inhibit osteoclast differentiation

Sung Eun Kim, Dong Hun Suh, Young-Pil Yun, Jae Yong Lee, Kyeongsoon Park, Jun-Young Chung, Deok-Won

Journal of Materials Science: Materials in Medicine, 2012

Co-delivery of platelet-derived growth factor (PDGF-BB) and bone morphogenic protein (BMP-2) coated onto heparinized titanium for improving osteoblast function and osteointegration

Sung Eun Kim, Young-Pil Yun, Jae Yong Lee, June-Sung Shim, Kyeongsoon Park, Jung-Bo Huh

Journal of Tissue Engineering and Regenerative Medicine, 2013

The effect of titanium with heparin/BMP-2 complex for improvingosteoblast activity

Su-Young Lee, Young-Pil Yun, Hae-Ryong Song, Heung Jae Chun, Dae Hyeok Yang,Kyeongsoon Park, Sung Eu

CARBOHYDRATE POLYMERS, 2013

Improvement of Osteoblast Functions by Sustained Release of Bone Morphogenetic Protein-2 (BMP-2) from Heparin-coated Chitosan Scaffold

Young-Pil Yun, Su-Young Lee, Hak-Jun Kim, Jae-Jun Song, Sung Eun Kim

Tissue Engineering and Regenerative Medicine, 2013

Fabrication and Characterization of PCL/TiO2 Nanoparticle 3D Scaffol

Jung-Ho Kim, Ok Joo Lee, Faheem A. Sheikh, Hyung Woo Ju, Bo Mi Moon,Hyun Jung Park, and Chan Hum Par

POLYMER-KOREA, 2014

3D silk fibroin scaffold incorporating titanium dioxide (TiO2) nanoparticle (NPs) for tissue engineering

Jung-Ho Kim, Faheem A. Sheikh, Hyung Woo Ju, Hyun Jung Park, Bo Mi Moon, Ok Joo Lee, Chan Hum Park

INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, 2014

Facile and highly efficient approach for the fabrication of multifunctional silk nanofibers containing hydroxyapatite and silver nanoparticles

Faheem A. Sheikh, Hyung Woo Ju, Bo Mi Moon, Hyun Jung Park, Jung-Ho Kim, Ok Joo Lee, Chan Hum Park

JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A, 2014

Development of Artificial Dermis Using 3D Electrospun Silk Fibroin Nanofiber Matrix

Ok Joo Lee, Hyung Woo Ju, Ji Heui Kim, Jung Min Lee, Chang Seok Ki, Jung-Ho Kim, Bo Mi Moon1, Hyun J

Journal of Biomedical Nanotechnology, 2014

A comparative mechanical and biocompatibility study of poly(ε-caprolactone), hybrid poly(ε-caprolact

Faheem A Sheikh, Hyung Woo Ju, Bo Mi Moon, Hyun Jung Park, Jung-Ho Kim, Soo Hyeon Kim, Ok Joo Lee an

JOURNAL OF BIOACTIVE AND COMPATIBLE POLYMERS, 2014

Dissolution of zinc oxide nanoparticles in exposure media of algae, daphnia, and fish embryos for nanotoxicological testing

Yu-Jin Shin, Woo-Mi Leea, Jin Il Kwak, Youn-Joo An

CHEMISTRY AND ECOLOGY, 2017

Quantification of silver nanoparticle toxicity to algae in soil via photosynthetic and flow-cytometric analyses

Sun-Hwa Nam, Jin Il Kwak, Youn-Joo An

Scientific Reports, 2018

Cystamine-incorporated gelatin microsphere and its redox-responsive release property

Tae Hoon Kim, Jin-Chul Kim

MOLECULAR CRYSTALS AND LIQUID CRYSTALS, 2017

Effects of silver nanowire length and exposure route on cytotoxicity to earthworms

Jin Il Kwak, June-Woo Park, Youn-Joo An

ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH, 2017

Pluronic-Induced Surface Etching of Biodegradable Nanofibers for Enhanced Adsorption of Serum Protein

Wei Mao, Hyuk Sang Yoo

MACROMOLECULAR BIOSCIENCE, 2017

Coaxial Electrospun Nanofibers with Different Shell Contents to Control Cell Adhesion and Viability

Jae KeunPark, Oanh VuPham-Nguyen, Hyuk SangYoo,

ACS Omega, 2020

Electrospun nanohybrid hydrogels for enhanced differentiation of myoblasts

WeiMao, SolLee, Song RaeKim, Kil NamKim, Hyuk SangYoo,

Journal of Industrial and Engineering Chemistry, 2019

Michael-Type Addition of Gelatin on Electrospun Nanofibrils for Self-Assembly of Cell Sheets Composed of Human Dermal Fibroblasts

Ju Won Lee and Hyuk Sang Yoo

ACS Omega, 2019

Vesicles Comprising Dimethylaminopropyl Octadecanamide, Stearic Acid, and Carboxyhexadecyl Disulfide and Their Release Property under Reducing Condition

Jin AhKim, Jin ChulKim,

BIOTECHNOLOGY AND BIOPROCESS ENGINEERING, 2020

Thiolated alginate microparticles exhibiting redox-responsive release

Tae HoonKim, Jin ChulKim,

International Journal of Polymeric Materials and Polymeric Biomaterials, 2020

Compartment-restricted and rate-controlled dual drug delivery system using a biosilica-enveloped ferritin cage

Mi RanKi, Jong KiKim, Sung HoKim, Thi Khoa MyNguyen, Kyung HeeKim, Seung PilPack,

JOURNAL OF INDUSTRIAL AND ENGINEERING CHEMISTRY, 2020

Light-Triggered Structural Modulation of Nanofibrous Meshes to Promote Deep Penetration of Cultured Cells

Oanh-Vu Pham-Nguyen, Ju Won Lee, Yeonju Park, Sila Jin, Song Rae Kim, Jongmin Park, Ju Hyun Park, Young Mee Jung, and Hyuk Sang Yoo*

MACROMOLECULAR BIOSCIENCE, 2022

Spray-dried microparticles composed of carboxylated cellulose nanofiber and cysteamine and their oxidation-responsive release property

Tae HoonKim, Seung HwanLee, Jin ChulKim,

COLLOID AND POLYMER SCIENCE, 2020

Fluorescence-Shadowing Nanoparticle Clusters for Real-Time Monitoring of Tumor Progression

Oanh-Vu Pham-Nguyen, JiUn Shin, Yeonju Park, Sila Jin, Song Rae Kim, Young Mee Jung, and Hyuk Sang Yoo*

BIOMACROMOLECULES, 2022

Production of TiO2-deposited Diatoms and Their Applications for Photo-catalytic Degradation of Aqueous Pollutants

ShipraKumari, Ki HaMin, Bashistha KumarKanth, Eui KyoungJang, Seung PilPack,

BIOTECHNOLOGY AND BIOPROCESS ENGINEERING, 2020

Electrospun Nanofibrils Surface-Decorated with Photo-Cross-Linked Hyaluronic Acid for Cell-Directed Assembly

Wanho Cho, Yeonju Park, Young Mee Jung, Ju Hyun Park, Jongmin Park, and Hyuk Sang Yoo*

ACS Omega, 2022

Rapid in situ biomonitoring of subsoil contamination by applying an algae-soaked disc seeding assay

Sun HwaNam, Jin IlKwak, Youn JooAn,

Applied Sciences-Basel, 2021

Real-Time Monitoring of Multitarget Antimicrobial Mechanisms of Peptoids Using Label-Free Imaging with Optical Diffraction Tomography

Minsang Kim, Yeongmi Cheon, Dongmin Shin, Jieun Choi, Josefine Eilsø Nielsen, Myeong Seon Jeong, Ho Yeon Nam, Sung-Hak Kim, Reidar Lund, Håvard Jenssen, Annelise E. Barron, Seongsoo Lee, and Jiwon Seo

Advanced Science, 2023

Nanofibril guided spheroid formation for enhanced pluripotency and differentiation of human induced pluripotent stem cells

조완호, 박진희, 김위진, Wei Mao, 박종민, 정영미, 박주현, 유혁

CHEMICAL ENGINEERING JOURNAL, 2024