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지역	서울서부센터
주소	(03759) 서울특별시 서대문구 북아현로 150 산학협력관 한국기초과학지원연구원
보유센터 및 부서	서울서부센터 오믹스분자시스템연구팀
장비담당자	방은정
전화	◀ 전화기 아이콘을 누르시면 전화번호를 볼 수 있습니다.
팩스	02-6908-6215
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Spec 및 활용분야

원리 및 특징	· 핵자기공명 (NMR, nuclear magnetic resonance)은 자기장 속에 놓인 특정 원자핵이 자성을 가지고 있는 경우 자기적 에너지를 갖게 되고, 그 에너지에 해당하는 주파수의 전자기파를 받게 되면 공명현상을 일으키고, 이를 전기적 신호로 측정함으로 분자들의 구조, 분자들간의 상호작용, 분자들의 동력성에 대한 정보를 얻을 수 있다. · HRMAS (High Resolution Magic Angle Spinning) probehead는 MAS 기법을 이용하여 고체 뿐만 아니라 반고체에 해당하는 gel 형태의 시료, 난용성 시료 등 광범위한 측정이 가능하며, 생체조직을 포함한 다양한 시료를 전처리 없이 고분해능과 고감도로 측정이 가능하다.
구성 및 성능	○ Magnet: 16.4 Tesla ○ Four channel system ○ z-Gradient (60 Gauss /cm) ○ Probeheads 5mm 1H(13C/15N) TXI-probe 5mm BBO-probe 1.7mm 1H(13C/15N) TXI-probe 4mm 1H(13C/15N) HRMAS-probe ○ Autosampler for liquid sample ○ Auto sample changer for MAS sample
활용분야	○ 생체조직, 생검시료, 미생물 등의 대사체 분석 ○ 30μl 이하의 천연물 등 제한적 용량 시료의 구조분석 ○ 난용성 물질의 1H-NMR 측정 ○ 유기화합물의 구조분석- 보유기기목록 및 사양 확인 후 담당자 직접 문의 - 분석상담 및 행정 문의 (02-6908-6231) - 분석완료 후 이메일 또는 전화 통보

A 1H HR-MAS NMR-Based Metabolomic Study for Metabolic Characterization of Rice Grain from Various Or

Eun-Hye Song, Hyun-Ju Kim, Jaesik Jeong, Hyun-Jung Chung, Han-Yong Kim, Eunjung Bang, and Young-Shick Hong

JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 2016

Novel Structural Components Contribute to the High Thermal Stability of Acyl Carrier Protein from Enterococcus faecalis

Park YG

Konkuk University, 2016

Novel Structural Components Contribute to the High Thermal Stability of Acyl Carrier Protein from Enterococcus faecalis

Young-Guen Park, Min-Cheol Jung, Hee Sang Song, Ki-Woong Jeong, Eunjung Bang, Geum-Sook Hwang, Yangm

JOURNAL OF BIOLOGICAL CHEMISTRY, 2015

GLYCOSYLATED METHOXYMACROLACTINS FROM A MARINE SEDIMENT BACTERIUM BACILLUS SUBTILIS

Hee Jae Shin, Fakir Shahidullah Tareq, Ji Hye Kim, Min Ah Lee, Hyi-Seung Lee, Yeon-Ju Lee, and Jong-Seok Lee

HETEROCYCLES, 2013

Bioactive Lignan Constituents from the Twigs of Lindera glauca

김기현, 문은정, 하상근, 서원세, 김호경, 김선여, 최상운, 이강노

Chemical and Pharmaceutical Bulletin, 2014

Two New Triterpene Saponins from the tubers of Stachys sieboldii

조현경, 김충섭, 서원세, 김기현, 이강노

HETEROCYCLES, 2014

Electrochemical Preparation of Ionic Liquid-Stabilized Palladium Nanoparticles

Jong-Ho Cha, Sun-Mi Park, Yeon Ki Hong, Hyunjoo Lee, Jeong Won Kang, Ki-Sub Kim

JOURNAL OF NANOSCIENCE AND NANOTECHNOLOGY, 2012

Fabrication of Metal Nanoparticles Using Hydroxylated Ionic Liquids

Kwangwon Lee, Sanghyun Kim, Da-Hee Han, Yeon Ki Hong, Hyunjoo Lee, Jeong Won Kang, Ki-Sub Kim

JOURNAL OF NANOSCIENCE AND NANOTECHNOLOGY, 2011

Dialysis modality-dependent changes in serum metabolites:accumulation of inosine and hypoxanthine in patients on haemodialysis

Ji-Young Choi1,8,*, Yoo Jeong Yoon2,*, Hee-Jeong Choi1,8, Sun-Hee Park1,8, Chan-Duck Kim1,8,

NEPHROLOGY DIALYSIS TRANSPLANTATION, 2011

A new triterpene glycoside from the stems of Lagerstroemia indica

우경완, 차준민, 최상운, 이강노

ARCHIVES OF PHARMACAL RESEARCH, 2016

Neuroprotective Fatty Acids from the Stem Bark of Sorbus commixta

김충섭, 서원세, Lalita subedi, 김선여, 최상운, 이강노

LIPIDS, 2016

Anti-inflammatory terpenoid derivatives from the twigs of Syringa oblata var. dilatata

Kyoung Jin Park, Lalita Subedi, Sun Yeou Kim, Kang Ro Lee

Phytochemistry Letters, 2018

Secoiridoid Glycosides from the Twigs of Ligustrum obtusifolium Possess Anti-inflammatory and Neuroprotective Effects

Won Se Suh, Oh Kil Kwon, Tae Hyun Lee, Lalita Subedi Sun Yeou Kim, and Kang Ro Lee

CHEMICAL & PHARMACEUTICAL BULLETIN, 2018

Two new steroidal alkaloids from the bulbs of fritillaria thunbergii

Won Se Suh, Seung Young Lee, Jong Eel Park, Dong Hyun Kim, Sun Yeou Kim, Kang Ro Lee

HETEROCYCLES, 2018

Three New Lignan Derivatives from Lindera glauca (Siebold et Zucc.) Blume

서원세, 김기현, 김호경, 최상운, 이강노

HELVETICA CHIMICA ACTA, 2015

Bioactive triterpenoids from twigs of Betula schmidtii

Kyoung Jin Park, Lalita Subedi ,Sun Yeou Kim, Sang Un Choi, Kang Ro Lee

BIOORGANIC CHEMISTRY, 2018

Ursane Saponins from the Stems of Firmiana simplex and their Cytotoxic Activity

우경완, 최상운, 김기현, 이강노

JOURNAL OF THE BRAZILIAN CHEMICAL SOCIETY, 2015

Lignan Glycosides from the Twigs of Chaenomeles sinensis and Their Biological Activities

김충섭, Lalita Subedi, 김선여, 최상운, 김기현, 이강노

JOURNAL OF NATURAL PRODUCTS, 2015

Phytochemical constituents of capsella bursa-pastoris and their anti-inflammatory activity

Joon Min Cha, Dong Hyun Kim, Tae Hyun Lee, Lalita Subedi, Sun Yeou Kim, Kang Ro Lee

Natural product sciences, 2018

Redox-responsive biodegradable nanogels for photodynamic therapy using Chlorin e6

김효용,김병재,이채연,린정민,홍성진,김진구,하은주,백현종

JOURNAL OF MATERIALS SCIENCE, 2016

Alkaloids of NIRAM, natural dye from Polygonum tinctorium, and their anti-inflammatory activities

Dong Hyun Kim, Chung Sub Kim, Lalita Subedi, Sun Yeou Kim, Kang Ro Lee

TETRAHEDRON LETTERS, 2019

Slow-Motion Self-Assembly: Access to Intermediates with Heterochiral Peptides to Gain Control over Alignment Media Development

Hye-soo Lee, Yong-beom Lim

ACS Nano, 2020

Chemical constituents of Impatiens balsamina stems and their biological activities

Dong Hyun Kim, Tae Hyun Lee, Lalita Subedi, Sun Yeou Kim, Kang Ro Lee

Natural Product Sciences, 2019

Promotion of 119-helical folding in αβ-peptides containing β^{2-homoalanine residue}

HyerimYoon, JaeyeonLee, PhiljaeKang, Soo HyukChoi,

Peptide Science, 2021

Helical Structures of Nylon-Like Oligomers Consisting of 1,2-Diamine and 1,2-Dicarboxylic Acid Building Blocks Containing a Five-Membered Ring Constraint

SunglimChoi, Ilia A.Guzei, YounghunKim, PhiljaeKang, Soo HyukChoi,

ChemPlusChem, 2021

Synthesis and conformational analysis of an anti-beta2,3-amino acid as a building block for unnatural peptide helices

Sunglim Choi, Soo Hyuk Choi

BULLETIN OF THE KOREAN CHEMICAL SOCIETY, 2022